What Should I Expect From a Proposed Treatment Course?
A proposed treatment course and its expectations are discussed openly; discussing them does not guarantee results, and uncertainty should be made clear.
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Microneedling Knowledge Hub
Evidence-informed guides to basics, safety, devices, concerns, evidence and regulation.
What Peer Review Can and Cannot Tell You About a Study
Peer review is the process of scrutiny before publication; it indicates review happened, and it does not guarantee validity, quality, efficacy, or safety.
Microneedling and Rosacea: What One Retrospective Study Reports
What one retrospective cohort study (n=160) reports about microneedling plus oral doxycycline for facial erythema in rosacea, and its limits.
How Can I Tell Health Information From Marketing?
Health information can be checked by its sponsor, purpose, currency, and support; this page explains those checks for telling information from marketing.
What Do Evidence Boundaries Mean Before I Decide?
Health information can be evaluated by checking who created it, why, and whether it is supported; this page explains those checks when deciding what...
Study Result vs Treatment Recommendation: Why They Are Not the Same
A study result is a finding; a treatment recommendation adds values and context. This page explains the difference and gives no recommendations.
Microneedling With Topical Therapy for Melasma: A Meta-Analysis
A meta-analysis examined microneedling with topical therapy for melasma. Review the findings, study differences, and evidence limitations.
Why Are Outcome-Based Subgroup Findings Exploratory?
Outcome-based subgroup findings, identified after a study is complete, are exploratory and should not be treated as pre-specified confirmatory results.
How Should I Discuss Procedure Claims With a Provider?
Shared decision making is a framework for discussing options, benefits, risks, and uncertainties; this page explains the framework without judging providers.
How Does Sample Size Affect What a Study Can Conclude?
Sample size shapes how precisely a study can measure an effect and its power to detect one; it does not by itself determine whether...
Microneedling for Facial Skin Laxity: What One Study Reports
A 48-adult open-label single-center study reported automated microneedling improved facial skin laxity at Day 150 (mean 1.09, 99% CI 0.93–1.26) and at Day 90.
Association vs Causation in Research: How to Tell the Difference
An association between two things does not by itself prove that one causes the other; this page explains why, with no disease or risk...
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