Statistically Significant Doesn't Mean Clinically Important
Statistically significant means an effect is unlikely to be due to chance; it does not tell readers whether the effect is clinically important.
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Microneedling Knowledge Hub
Evidence-informed guides to basics, safety, devices, concerns, evidence and regulation.
Microneedling With Triamcinolone for Burn Scars: A Study
A small study examined microneedling with triamcinolone for burn scars. Review its design, findings, and important evidence limitations.
When a Study Is Only an Abstract: What Readers Should Know
When a study is published only as an abstract, readers have a summary, not the full report; an abstract alone may not provide enough...
Microneedling Contraindications: Who the FDA Advises Against Treatment
Who the FDA advises against microneedling: known malignancy, cancer treatment, pregnancy, breastfeeding, and stainless steel or anesthetic allergies.
Microneedling Aftercare and Reactions During the First Week
Reported first-week reactions after microneedling and evidence-bounded aftercare boundaries: typical timelines, gentle care, and what is not guaranteed.
Microneedling Infection Risk: What Safety Evidence Says
What safety reviews say about active skin infection as a risk factor for microneedling adverse effects, with no diagnosis or disinfection protocol.
FDA Classification of Powered and RF Microneedling Devices
The FDA regulatory distinction between ordinary powered microneedling devices and the specific Define RF Microneedling System record.
Scalp Microneedling for Hair Loss: Current Evidence
Current evidence on scalp microneedling for hair loss: a 24-week trial in 60 men, a 27-trial network meta-analysis, and combination results.
Microneedling for Acne Scars: What the Evidence Shows
What the evidence shows about microneedling for atrophic acne scars: combination findings, study-specific results, and what the research does not show.
How Microneedling Works: Micro-Injuries and Skin Remodeling
Microneedling creates controlled micro-injuries in the skin. Learn how studies describe the healing response and the limits of current evidence.
What Is Microneedling (Collagen Induction Therapy)?
What is microneedling? A neutral definition of the technique, the clinical names it goes by, and what the evidence supports — no product or...
Questions to Bring to a Procedure Consultation
Preparing a short list of questions before a consultation is a communication tool; asking them during the visit helps you get the information you...
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